International Journal of Current Microbiology and Applied Sciences
ISSN: 2319-7706 Volume 2 Number 8 (2013) pp. 296-302
Green synthesis of Flavanone by Using Ionic Liquid EAN (Ethyl Ammonium Nitrate)
Arshia Parveen*
*Department of Chemistry, B.Raghunath College, Parbhani-431401(MS), India *Corresponding author e-mail: arshiachemistry@yahoo.co.in; arshiairfanmalik@gmail.com
A B S T R A C T
A high yielding and efficient method for smooth conversion of substituted - - unsaturated carbonyl compounds (E) chalcones to corresponding substituted 2- phenylchroman-4-one i.e. flavones promoted by ionic liquid catalyst, ethyl ammonium nitrate [EtNH3]NO3 under microwave irradiation in excellent yield with shorter reaction time . The ionic liquid can be recycled and reused several times. Flavanone was synthesized and tested for antibacterial effects against Bacillus Subtilis, Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. The antibacterial screening of the synthesized compounds were performed in vitro by the filter paper disc diffusion method.
Keywords
Dehydrate cyclization; - -unsaturated antibacterial activity; Flavanone