International Journal of Current Microbiology and Applied Sciences
ISSN: 2319-7706 Volume 2 Number 7 (2013) pp. 207-216
Antibacterial activity of protein extract of marine Pseudomonas aeruginosa against bacterial pathogens
D. Jayammal and T. Sivakumar*
Department of Microbiology, Kanchi shri Krishna College of Arts and Science, Kilambi -631 551, Kancheepuram, Tamil Nadu, India *Corresponding author:
Antimicrobial substances are so widespread that they are likely to play an important protective role. Marine bacterium has been recognized as important antimicrobial substances producers which have an exceedingly bright future in the discovery of life saving drugs. Wet soil samples were collected from marine resource for the isolation of bacteria. 4 bacteria s of Pseudomonas were isolated based on their morphological and structural characteristics. They were screened for antibacterial activity against bacterial pathogens by point inoculation and agar well diffusion method. Screening for antibacterial activity of the supernatant of A was also done. In all the screening processes isolate showed zone of clearance of 12mm. The marine isolate was identified by as Pseudomonas aeruginosa. From the present study it has been concluded that the antimicrobial substances from Pseudomonas aeruginosa has greater antibacterial activity against bacterial pathogens than Bacitracin and tetracycline. The findings of this surveillance study will enhance our knowledge regarding the problem of antimicrobial resistance and will serve as a basis for future development of new anti bacterial pathogens substance against new resistance in bacterial pathogens.
Antimicrobial substances; Pseudomonas aeruginosa; antibacterial activity; antimicrobial resistance.