International Journal of Current Microbiology and Applied Sciences
ISSN: 2319-7706 Volume 2 Number 10 (2013) pp. 154-171
Study of Polyphenolic Extracts of Prunus Domestica L. Wall Nuts As Hypolipidemic Agents
Ali B. Roomi, Raid M. H. Al-Salih* and Husam M. Kredy
Chemistry Dept. College of Science Thi-Qar University
The goal of this study is to investigate the effect of polyphenolic in order to extract Prunus domestica red (PDR) and Prunus domestica yellow (PDY) wall nuts on some physiological and biochemical parameters in female rats in vivo and anti- bacterial activity in vitro. The working of this thesis involves the following terms: Analytical study: the Analytical study demonstrates the presence of polyphenols in PDR and PDY. The UV-Vis Spectra and high performance liquid chromatography of extracted poly-phenolic are proved for presence of (Tannic acid, Gallic acid, Caffeic acid, Vanillic acid, Ferulic acid, amygdalin, Chlorogenic acid). Bio- chemical parameters: all rats in Bio-chemical parameters are divided into normal control group (A), hyperlipidemia positive control group (B), and the rest of the two groups (C & D) are served as experimental groups. Group(C) of hyperlipidemic experimental rats received the extracted poly-phenolic of PDR at 25 mg/kg of body weight for 30 days on daily basis. While group (D) rats is received the extracted poly-phenolic of PDY at 25 mg/kg of body weight for 30 days on daily basis. Whilst blood samples collects after 30 days. Lipid profile: the positive hyperlipidemic control group s rats showed variable increases in serum triglycerides, LDL, VLDL and total cholesterol levels. Serum HDL levels are decreases in positive hyperlipidemic control groups. PDR and PDY are significantly decreased the levels of these parameters in rats. Consequently the PDR reduces the lipid levels more and in effectively way than PDY do.
Prunus domestica L.; polyphenols; Wall Nuts; hypolipidemic.