National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Enteric microbial agents in HIV differ in several ways between developing and developed world, the awareness of which can often guide appropriate prevention and patient treatment when limitation of resources prevent laboratory diagnosis of exact etiological agent. The primary objective of this study was to define and compare enteric bacterial pathogens in HIV-1 infected with diarrheal symptoms and non-HIV infected controls with diarrheal symptoms at a tertiary care hospital in northern India. This prospective study was conducted between January 2014 and December 2015 of a tertiary care academic health organization of North India. Stool samples from 300 HIV seropositive cases with diarrhea (study group) and 600 HIV negative diarrhea cases (control group) were examined. Samples were inoculated onto standard culture media. All the isolates were tested for antimicrobial susceptibility. Out of 300 HIV seropositive cases with diarrhea, 114 (38%) were positive for bacterial pathogens whereas in 600 HIV seronegative with diarrhea controls 120 (20%) were positive for bacterial pathogens. 41 isolates of Diarrheagenic Escherichia coli, 24 Campylobacter jejuni, 10 Aeromonas hydrophilia, 16 Shigella spp., 9 Salmonella spp., and 14 Yersinia enterocolitica were recovered from the HIV infected cases. Most of the bacteria were resistant to nalidixic acid. There is underline need for epidemiological investigations to screen microbial etiological agents in HIV infected subjects with diarrhoea along with their antibiogram periodically for reduction of morbidity and mortality in these patients.
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