International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:9, September, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(9): 1637-1642

Immunopathological Evaluation of Protective Potential of Cajanus indicus on Aflatoxin Induced Toxicity in Broilers
N. Sahu1, M. Mondal2*, R.C. Ghosh1 and Shonam Tamrakar1
1Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Chhattisgarh Kamdhenu Vishwavidyalaya, Durg, Chhattisgarh, India
2Department of Veterinary Clinical Complex, F/O- Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, Kolkata, India
*Corresponding author

The aim of the present study was to elucidate the protective potential of herb, Cajanus indicus on aflatoxin (AF) induced immunopathological alterations in commercial broilers. A total of 168 Vencobb day old broiler chicks were randomly divided into four equal groups of 42 each. Group I broilers were given plain feed and served as control whereas, group II and III were given Cajanus indicus leaf powder (CLP) @ 2 g/kg and AF @ 1 ppm with normal feed respectively. Group IV broilers were fed on diet containing AF @ 1 ppm and CLP @ 2 g/kg for 42 days. The results revealed a significant (P≤0.01) increase in skin thickness in the control groups I and II at 24 and 48 hrs post challenge (1% Dinitroflurobenzene in vehicle) as compared to intoxicated groups III and IV. AF toxicity significantly reduced the development of humoral immune response in broilers and supplementation of C. indicus could partially protect the reduction in HA titers of AF intoxicated broilers. Aflatoxicosis significantly suppressed the both cell mediated and humoral immune responses. But CLP supplementation had a potent immunomodulatory effect. So, it helps not only in controlling aflatoxicosis but also can play a pivotal role in correcting chicken immune dysfunction.

Keywords: Broiler, Immunopathology, Aflatoxicosis

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How to cite this article:

Sahu, N., M. Mondal, R.C. Ghosh and Shonam Tamrakar. 2018. Immunopathological Evaluation of Protective Potential of Cajanus indicus on Aflatoxin Induced Toxicity in Broilers.Int.J.Curr.Microbiol.App.Sci. 7(9): 1637-1642. doi:
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