International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:9, September, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(9): 1630-1636

Immunotoxic Effect of Selenium Following Subacute Exposure in Broilers
Shonam Tamrakar1, M. Mondal2*, R.C. Ghosh1 and N. Sahu1
1Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Chhattisgarh Kamdhenu Vishwavidyalaya, Durg, Chhattisgarh, India
2Department of Veterinary Clinical Complex, F/O- Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, Kolkata, India
*Corresponding author

This study was conducted with an objective to determine the immunotoxic effect of sub acute exposure of selenium (Se) in broilers with special reference to the Dinitroflurobenzene (DNFB) contact skin sensitivity test and pathomorphological alterations in histoarchitecture of lymphoid organs. The chicks were intoxicated orally with sodium selenite @ 2, 6 and10 ppm respectively in diet, daily for 35 days. The present study exhibited significant depression of cell mediated immunity in Se treated broilers as measured by DNFB skin contact sensitization test. The blood picture revealed dose dependant heterophilia and leukocytopaenia due to lymphocytopaenia. During subacute Se toxicity, severity of pathological changes of treated broilers was dose dependent. Lymphoid organs of selenium treated broilers revealed severe depletion of lymphocytes from the germinal centre.

Keywords: Broiler, Immunotoxicity, Selenium

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How to cite this article:

Shonam Tamrakar, M. Mondal, R.C. Ghosh and Sahu, N. 2018. Immunotoxic Effect of Selenium Following Subacute Exposure in Broilers.Int.J.Curr.Microbiol.App.Sci. 7(9): 1630-1636. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.