National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study aimed for the identification of Curcuma amada in terms of biological activity with special emphasis to Anti-angiogenesis and anti cancer activity. The preliminary screening of the plant revealed the presence of different class of compounds in the rhizome extracts of Curcuma amada. These phytochemical compounds were identified on the basis of the screening tests showed the presence of the alkaloids, glycosides and anthraquinones. The precipitation test showed the presence of gum and mucilage in moderate quantitiy. The major quantity of active compounds was alkaloids while minor quantity of glycosides and anthraquinones was found. The rhizome extracts of Curcuma amada showed the presence of the phytochemical compound such as carbohydrates, phenols, flavonoids, tannins, steroids, terpenoids, saponins while absence of phenols, amino acids, oils and fats. The research studies showed that the crude form of rhizome Curcuma amada had more activity than peterolium ether extract, methanol extract and chloroform extract of rhizome Curcuma amada. The fertilized egg inoculation signified to identify which extracts of rhizome Curcuma amada have more activity. From this study it was identified that the crude form rhizome Curcuma amada had more anti-angioganesis activity than the peterolium ether, methanol and chloroform extracts. The anti-angiogenesis activities of drug 4-hydroxy benzaldehydes on the fertilized eggs were compared with the anti-angiogenesis activity of Curcuma amada in the fertilized egg. The in-vitro study supports the in-vivo studies. MTT assay in-vitro study reveals an anti-cancer activity of the crude form. The work reveals that the plant is a highly biological potent against cancer and further phytochemical investigation is to be initiated.
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