National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Drug resistance is a burning issue for bacterial isolates and in- appropriate use of antibiotics is one of the most important factors that could affect the increasing patterns of resistance. A predictable bacterial profile and antibiotic sensitivity will be of great help for clinicians to start empirical treatment. Hence periodical monitoring of bacterial profile and their antibiotic susceptibility pattern is important. Various clinical samples were obtained from 70 subjects from various departments of Hospitals which are associated with Dr. S. N. Medical College, Jodhpur, Western Rajasthan using aseptic methods and were processed in the laboratory immediately by using standard microbiological procedures. The bacterial isolates were identified by Gram’s staining and Vitek-2 compact automated system. The AST pattern of the isolates was also obtained by Vitek-2 compact automated system. Culture positivity in males was60.00% and 40.00% in females (M:F=3:2).Analysis of samples by Vitek-2 revealed that Staphylococcus aureus (40%) was the most common bacterial isolate followed by Enterococcus spp. (37.14%) and CONS (Coagulase negative Staphylococcus aureus) (22.85%). Among S. aureus16 (57.14%) were found to be Methicillin resistant Staphylococcus aureus (MRSA). The AST pattern showed that Tigecycline (58.33%), Nitrofurantoin (45.96%) and Vancomycin (40.36%) were the most susceptible drugs for the above isolates Changing antimicrobial resistance pattern poses challenge in treating pyogenic infections. It is very important to reduce frequent misuse; inadequate dosages and easy availability of antimicrobials to avoid antibiotic resistance. This study will thereby guide the clinician in choosing appropriate antibiotics which not only contributes to better treatment but their judicious use will also help in preventing emergence of resistance to the drugs which are still sensitive. Identification and AST pattern of bacterial isolates by Vitek-2 compact system is of great help to the clinicians as compared to the standard methods used, the use of Vitek-2 compact system would reduce the turnaround time by at least 16 hrs.
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