National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Aqueous extracts of Euphorbia hirta were used to study the anticlastogenic activity by in vivo rodent micronucleus assay. Mice were administrated two doses, 250 mg/kg and 500 mg/kg orally for a period of seven days and at the end of the seventh day, cyclophosphamide (50 m/kg) was given intraperitoneally. Bone marrow sample were analysed for cytotoxicity and micronucleus. Both the doses were not cytotoxic and clastogenic. There was a significant reduction in the micronucleus formation in bone marrow indicating the anticlastogenic activity of E. hirta.
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