National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Lower Respiratory tract infections (LRTI’s) are the most frequent infections among patients. The consequences of increased drug resistance are far reaching since bacterial infection of the respiratory tract (RT) is a major cause of death from infectious disease. The present study was conducted to determine the bacterial etiology and their antimicrobial susceptibility pattern of Gram negative bacteria in lower respiratory tract infections so as to update the clinicians in the various antimicrobial alternatives available in the treatment. Patients with lower respiratory tract infections were collected in time span of six months. Bacterial pathogens were isolated from sputum and tracheal specimens, and subjected to antibiotic susceptibility testing, using standard bacteriologic techniques. Out of samples obtained from 442 patients, 150 (33.93%) were culture positive. 315 samples yielded no growth. 127 were Gram-negative bacilli (GNB-28.73%). 23 were Gram positive cocci. The common GNB isolates were non-fermentative gram-negative bacilli Pseudomonas aeruginosa (34.64%), followed by Klebsiella spp. (31.49 %) and Acinetobacter spp. (15.74%). GNB isolates from sputum and endotracheal aspirates were 85 (66.92 %) and 42 (33.07 %) respectively. Maximum no. of patients were from 46-60 age group (35.43 %) followed by 61-75 age group (25.98%).Gram negative isolates showed high susceptibility with Colistin, Imipenem, Ciprofloxacin, Gentamicin, Levofloxacin, Amikacin. For effective management of LRTIs bacteriological diagnosis and antibiotic susceptibility pattern is indispensable.
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