National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The GeneXpert MTB/RIF (GeneXpert) test, a nucleic acid amplification test for the diagnosis of pulmonary tuberculosis in both HIV seronegative and serpositive patients is gradually replacing sputum smear microscopy even in resource-constrained developing nations. To assess the prevalence of GeneXpert sputum positive TB and sero-prevalence of human immunodeficiency virus (HIV) among patients with presumptive pulmonary tuberculosis (PTB) in a teaching hospital in North central Nigeria. This was an operational based prospective laboratory study carried out from Febraury, 2014 to May, 2015 at the Benue State University Teaching Hospital, Makurdi, North-central Nigeria. The GeneXpert technology and Determine/Stat pak were used for the diagnosis of PTB and HIV respectively. Three hundred (300) presumptive PTB cases were recruited, 160 (53.3%) were males and 140 (46.7%) were females. Mean age of 39.81 years. Seventy (23.3%) tested positive for PTB. More than half (56.3%) were positive for HIV with females most vulnerable. PTB/HIV co-infection was found in 34/300 (11.33%) of the patients. The positivity for PTB, HIV and co-infection were all skewed to age group of 31-40 years. The study revealed a high prevalence of GeneXpert sputum positive PTB, HIV and co-infection among presumptive PTB cases in Makurdi.
Citations |
 |
 |
 |
 |
