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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:5, May, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(5): 2045-2051
DOI: https://doi.org/10.20546/ijcmas.2018.705.240


Ameliorative Potential of Mentha piperita against Arsenic Trioxide Induced Geno-Toxicological Alteration in Fish, Channa punctatus (Bloch.)
Shraddha Dwivedi*
Environmental Toxicology & Bioremediation Laboratory (ETBL), Department of Zoology, University of Lucknow, Lucknow-226007, India
*Corresponding author
Abstract:

Present study aims to evaluate the amleorative potential of Mentha piperita (MP) against arsenic trioxide (ATO) in freshwater fish Channa punctatus (Bloch). Fish were divided into six groups. G1 served as control. Fish of G2 and G3 were treated with 96 h-LC50/10 of ATO and 8 mg/l of MP, respectively. In G4, G5 and G6, fish were given simultaneous treatment of 96 h-LC50/10 of ATO along with 2 mg/l, 4 mg/l, and 8 mg/l concentrations of MP. Samples collected at the interval of 24 h till 96 h exposure period. Result reveals an increased frequency of micronuclei (MN) in G2 on comparing with the G1. However in groups G4, G5 and G6, where fish were exposed to ATO along with 2 mg/l, 4 mg/l, 8 mg/l of MP respectively were showing reduction in frequency of micronuclei (MN). This reduction in frequency of MN on introduction of MP must be due to phyto-chemicals present in the MP extract. This has been proved by the presence of well-known antioxidants viz., alkaloids, flavonoids, saponin and tannins in photo-chemical tests.


Keywords: Mentha piperita, Channa punctatus, Arsenic dioxide, Amelioration, Micronuclei

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How to cite this article:

Shraddha Dwivedi. 2018. Ameliorative Potential of Mentha piperita against Arsenic Trioxide Induced Geno-Toxicological Alteration in Fish, Channa punctatus (Bloch.).Int.J.Curr.Microbiol.App.Sci. 7(5): 2045-2051. doi: https://doi.org/10.20546/ijcmas.2018.705.240
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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