National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Soil is a richest source of microorganisms. These have played a significant role in antibiotic discovery. Though, thousands of antibiotics were discovered from soil microorganisms, very few were potent or old antibiotics loss their potency or few pathogens became multiple drug resistance. To solve these problems one has to discover new antibiotics to control pathogens. Hence, selective isolation of rare microorganisms from soil may allow the discovery of new antibiotics. Therefore they were isolated and screened for antibiotic production & to find their inhibitory effects on pathogens. It was observed that, two colonies (C2 & C4) of seven antibiotic producing bacterial colonies were identified as P. aeruginosa strain-1(C2) & strain-2(C4), and remaining unknown colonies were named as C1, C3, C5, C6 & C7. Out of seven bacteria isolated, antibiotics of C1 has inhibition effect on growth of E. coli; C2 on E. coli, P. aeruginosa & S. aureus; C3 & C5 on S. aureus; C4, C6 & C7 on E . faecalis, Further, each of soil bacteria antibiotics shown varied degree of antibiotic effects on different pathogens. C4 has highest inhibitory effect of the growth of E. faecalis; followed by C5 on S. aureus and C2 on P. aeruginosa. The antibiotic effect of some selected soil bacteria, and commercial streptomycin antibiotic has almost equivalent affect on four studied pathogens.
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