Understanding the Molecular Relationship between Foot-and-Mouth Disease Virus Serotype O of Indian Vaccine Strain with Strains across the World by Phylogenetic Analysis

Vishweshwar Kumar Ganji; Sampath Kontham; Mallesh Pottabathula

doi:https://doi.org/10.20546/ijcmas.2018.705.013

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Original Research Articles Volume : 7, Issue:5, May, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
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Int.J.Curr.Microbiol.App.Sci.2018.7(5): 99-105

DOI: https://doi.org/10.20546/ijcmas.2018.705.013

Understanding the Molecular Relationship between Foot-and-Mouth Disease Virus Serotype O of Indian Vaccine Strain with Strains across the World by Phylogenetic Analysis

Vishweshwar Kumar Ganji^1*, Sampath Kontham² and Mallesh Pottabathula³

¹FMD Research Lab, Indian Veterinary Research Institute, Bengaluru, Karnataka-560024, India
²Department of Animal Genetics and Breeding
³Department of Veterinary Parasitology, C.V.Sc, PVNR Telangana Veterinary University, Hyderabad, Telangana-500030, India

^*Corresponding author

Abstract:

Foot-and-mouth disease is one of the important animal virus known to be highly infectious and causing a serious trade barrier. For effective control of FMD there is a need for in depth understanding of the virus epidemiology. The present study has been undertaken to understand the molecular relationship between the strains across world in comparison to Indian vaccine strain and virus isolate of 2010. The study is done by comparing the nucleotide sequence of VP1 protein, known to induce neutralizing antibodies by phylogenetic analysis. Based on phylogenetic analysis we found that the disease in India is mainly caused by transboundary evolution of virus but not due to the vaccine strain.

Keywords: FMD, Virus, Phylogeny, Epidemiology, Molecular characterization

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How to cite this article:

Vishweshwar Kumar Ganji, Sampath Kontham and Mallesh Pottabathula. 2018. Understanding the Molecular Relationship between Foot-and-Mouth Disease Virus Serotype O of Indian Vaccine Strain with Strains across the World by Phylogenetic Analysis.Int.J.Curr.Microbiol.App.Sci. 7(5): 99-105. doi: https://doi.org/10.20546/ijcmas.2018.705.013

Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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Original Research Articles Volume : 7, Issue:5, May, 2018

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