National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
In the present study the ethanol extracts of Capparis sepiaria, Euphorbia heterophylla and Tamilnadia uliginosa leaf were tested for cytotoxic activity against three different human cancer cell lines such as HeLa cervical cancer cell line, MCF-7 human breast adenocarcinoma cell line and A-549 Human lung adenocarcinoma epithelial cell line, and compared with vero normal cell line. These studies revealed that Tamilnadia uliginosa crude extracts exhibited potent cytotoxic activity towards A-549 cell line with CTC50 value of 164.3 µg/ml followed by 179.4 µg/ml against MCF-7 cell lines and 208.2 µg/ml against HeLa cell lines. The leaf extracts of Euphorbia heterophylla showed least cytotoxicity against the tested cell lines. The results indicate the feasible anticancer nature of the crude ethanolic extract of Tamilnadia uliginosa leaves.
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