National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Observation of Keratin pearl (KP) and individual cell keratin (ICK) is a major criteria in histopathological grading of oral squamous cell carcinoma (SCC). The aim of the study was to evaluate and compare the distinct staining and identification of KP and ICK by routine Hematoxylin & Eosin (H&E) stain and modified Mallory’s stain. The known cases of oral SCC with sufficient paraffin embedded tissue were selected. The two sections from each block were stained with H&E stain and modified Mallory’s stain. The modified Mallory’s stain distinctively and clearly stained KP and ICK compared to H&E stain. The positive staining of KP and ICK by modified Mallory’s stain was statistically significant with P=0.001, f=0.001 and P=0.022, f=0.034 than H&E stain. Based on our observation we conclude that the positive staining of KP and ICK in oral SCC by modified Mallory’s stain is statistically significant than H&E stain. So, modified Mallory’s stain can be used as an adjuvant stain along with H&E stain in case of oral SCC.
Citations |
 |
 |
 |
 |
