National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Aim of the to assess the purpose of fungal rhinosinusitis at MNR Medical College & Hospital, Sangareddy, and to correlate histopathological findings with culture results for accurate clinical classification of the disease. 217 suspected patients were included in the study. The relevant clinical details of the patients including the co-morbidities in the medical records were examined. Samples like nasal swabs collected during nasal endoscopy under sterile conditions, Sinus washings, Allergic mucin, tissue biopsy from polyps & tissue biopsy taken from sinus mucosa during nasal surgery, were processed and examined by microbiology culture using recommended techniques. Slide culture was done to observe the microscopic morphology. Histopathological examination was done by H and E stain and PAS stain for classification. Out of 217 cases of rhinosinusitis, 37 samples showed fungal isolates in culture. Aspergillus flavus was the most common isolate (8.29%). Aspergillus fumigatus was the second most common isolate (5.99%). Candida albicans was isolated in one sample and candida species, other than albicans was isolated in one more sample. On the basis of the histopathological findings, the fungal isolates were grouped. Among the 37 patients with fungal rhinosinusitis 26 patients belonged to non-invasive type. They were mostly of allergic etiology. The organisms were mostly Aspergillus fumigatus and Aspergillus flavus. Isolates that cause fungal ball were not isolated. 11 isolates belonged to invasive group. Most of them were Aspergillus flavus causing chronic granulomatous fungal sinusitis Mycological profile of rhinosinusitis at MNR Medical College, Sangareddy was thus evaluated. Histopathological and microbiological findings reported 37cases of fungal rhinosinusitis among 217 suspected cases of rhinosinusitis.
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