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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:2, February, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(2): 817-822
DOI: https://doi.org/10.20546/ijcmas.2018.702.103


Seroprevalence of Helicobacter pylori among Healthy Blood Donors
D. Ramya Priyadarshini1*, Joshy M. Easow2 and R. Vinod1
1Department of Microbiology, Sri Venkateshwara Medical College Hospital and Research Centre (SVMCHRC), Puducherry, India
2Department of Microbiology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India
*Corresponding author
Abstract:

Helicobacter pylori induces chronic inflammation of the underlying gastric mucosa causing gastritis and other complications. H. pylori infection once acquired is believed to persist lifelong unless treated. This is a cross-sectional epidemiological study to find the prevalence of the infection in asymptomatic healthy blood donors attending the SVMCHRC blood bank, Puducherry. Analysis of the sera from 99 apparently healthy subjects, based on the serological determination of the IgM and IgG antibodies against H. pylori, was carried out using a commercially available kit ELISA. There were 59 (60%) males and 40 (40%) females with the age range of 18 to 60 years. Overall seropositivity to Helicobacter pylori among healthy blood donors was 29.2%.8 (8.08%) subjects were positive for IgM, 21 (21.2%) subjects were positive for IgG. Age distribution of H. pylori infection showed increasing trend in the young age (21-25 years). A moderate increase in the prevalence of H. pylori infection among smokers was noticed. Among Tea/Coffee consumers 25(28.7%) showed the presence of antibody. Among 26 alcoholics involved in this study only 8 were found to be positive for IgG and IgM antibodies. Individuals living with low socioeconomic conditions had high prevalence rates of H. pylori.


Keywords: Helicobacter pylori, Blood donors, Seropositivity, Puducherry

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How to cite this article:

Ramya Priyadarshini, D., Joshy M. Easow and Vinod, R. 2018. Seroprevalence of Helicobacter Pylori among Healthy Blood Donors.Int.J.Curr.Microbiol.App.Sci. 7(2): 817-822. doi: https://doi.org/10.20546/ijcmas.2018.702.103
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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