National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Urinary tract infections are one of the most common bacterial infections in humans, both in the community as well as in the hospital settings. This study shows the changing antibiotic resistance pattern is pertinent for an appropriate treatment, prevention and control of the different mechanisms of resistance. Aim of this study was Detection of ESBL and AmpC in multidrug resistant uropathogenic E.coli and Klebsiella spp. E.coli & Klebsiella spp. were isolated by conventional method from 115 urine samples received in department of microbiology from Oct.2012 to Sept. 2013. The antimicrobial susceptibility to various drugs was studied by the disc diffusion method, by following the CLSI guidelines. Isolates were diagnosed for ESBL and AmpC production by phenotypic method i.e. Phenotypic Confirmatory Test for ESBL and Modified Hodge test using Cefoxitin disk for AmpC production. Total 115 isolates were collected for the study (E.coli-87 & Klebsiella spp-28), of which 52(45.21%) isolates were resistant to third generation cephalosporin. Out of 52 isolates, 28(53.8%) were ESBL producers and 13(25%) were AmpC producers.08 (21.1%) isolates were negative by both tests. From our study we concluded that it is essential to report ESBL and AmpC β-lactamase production along with the routine susceptibility testing, which will help the clinicians in prescribing antibiotics.
Citations |
 |
 |
 |
 |
