National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Isoflavones are one of the various phytochemicals present in soybean considered responsible for its health benefits. Isoflavone come under the class of polyphenolic compounds and are of different chemical forms. In soybean genistein, daidzein and their glycosidic forms are the major isoflavones present. In addition to these small amounts of glycitein and its derivatives are also present. A branch of phenyl propanoid pathway is responsible for isoflavone biosynthesis from simpler precursors. Isoflavone synthase is the key enzyme of this pathway. After action of this enzyme other modifications like glycosylation and malonylation can occur. Due to its structural similarity to estrogens, isoflavones show agnostic and sometimes antagonistic activity, which is considered responsible for anti-cancerous properties of soybean. However, bioavailability is a key factor for bioactivity. The use of microbial fermentation/isolation of efficient hydrolyzing enzymes can make the isoflavones more bioavailable in human digestive system.
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