Cellular immune status in Brucellosis affected and/or vaccinated cattles were studied by enumeration of total leukocytes, neutrophils and lymphocytes in peripheral blood. The mean leukocyte count in Brucellosis affected cattle which had been vaccinated during calf hood (IV) was 8.137 x 103/μl. In case of naturally infected cattle that had never been vaccinated (IU), the leukocyte count was 11.76 x 103/μl. In case of normal healthy vaccinated (HV, uninfected by Brucellosis) cattle, the leukocyte count was 6.84 x 103/ μl whereas in case of normal healthy unvaccinated (HU) calves, leukocyte count was 11.10x 103/μl. The mean neutrophil count (percent) was 38.25 + 6.50 in IV cattle and 30 + 5.36 in IU cattle. The neutrophil count was 17 + 3.22 in HV cattle and 15.5 + 4.9 in case of HU calves. The mean lymphocyte count (percent) was 39.625 + 9.14 in IV cattle and 51 + 5.58 in IU cattle. The lymphocyte count was 27 + 4.56 in HV cattle and 26.166 + 4.87 in HU calves. Leukocyte levels were very significantly (p<0.01) higher in IU compared to IV and HV cattle. In contrast, Neutrophil levels were significantly (p<0.05) higher in IV compared to IU cattle and very significantly (p<0.01) higher than HV cattle. Lymphocyte levels of IU cattle were significantly (p<0.05) higher than IV cattle and very significantly (p<0.01) higher than HV cattle.

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