National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
In recent years, the prevalence of infections with multidrug resistant Enterobacteriaceae has steadily increased. Enterobacteriaceae producing AmpC β-lactamases (AmpCs) have become a major therapeutic challenge. The detection of AmpC-producing Proteus mirabilis is of significant clinical relevance, as this may lead to inappropriate antimicrobial regimens and therapeutic failure. The aim of this study is to evaluate and comparing routinely phenotypic methods in detection of resistance with molecular methods. From this study, it can be concluded that cephamycin-Hodge test is the most sensitive, specific, interpretable and efficient test for detection of AmpC β-lactamases in clinical isolates of Proteus mirabilis, compared to the molecular method.
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