An experiment was conducted on three hundred broiler chicks divided into five groups of three replications each and reared upto six weeks of age on deep litter system. The control group (T1) was fed on corn soya based diet. Whereas T2, T3, with five percent reduction of energy and protein level than that of standard diet with supplementation of protease and xylanase enzymes, each at the rate of 100 g/ton of feed in T2 and 200 g/ton of feed in T3, however T4, T5 were fed on ten percent reduction of energy and protein level than that of standard diet with supplementation of protease and xylanase enzymes, each at the rate of 100 g/ton of feed in T4 and 200 g/ton of feed in T5. The body weights gain were significantly (P<0.01) higher on supplementation of protease and xylanase each @ 200 g/ton feed with reduced energy and protein levels by 5 percent in the diet than that of control. The feed consumption and FCR did not vary significantly amongst the groups. The DM and CP metabolizability was significantly better on supplementation on enzyme even on reduction in energy and protein in the diet either at 5 or 10 percent. The dressing percentage was more when enzymes were supplemented in 5 percent energy, protein deficient diet. The intestinal length was also reduced significantly due to enzyme supplementation on energy protein deficient. The E coli count was significantly (P<0.01) higher in control group and were lower in energy protein deficient diet with enzyme supplementation. Significantly lower serum total protein, albumin and globulin were observed due to reduction in energy and protein in the diet even after supplementation of enzymes xylanase and protease. The highest net profit per kg was obtained in T3 group. It was concluded that the supplementation of protease and xylanase @ 200g/ton each with reduction in energy and protein levels by 5 percent in broiler diet could be economical.

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