National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
To investigate the changes that occur in inflammatory mediators and reproductive hormones levels in mastitis crossbred cows, the crossbred cows were screened for SCM incidence (24) by mCMT, SCC, electric conductivity of milk and abnormal milk. Based on this, the cows were divided as group I (n=8) - no clinical symptom of mastitis (healthy), group II (n=8) - showing chronic sub-clinical mastitis (SCM), group III (n=8) - showing clinical mastitis symptoms (CM). Blood samples were collected from group I and II the cows at weekly intervals from day 54 to 138 of lactation. A single blood sample was collected from group III before giving antibiotic treatment. Plasma Nitric Oxide (NO), Interleukin-8 (IL-8), Tumor Necrosis Factor- α (TNF-α), cortisol and prostaglandin (PGFM) levels were higher (P<0.001) in clinical mastitis cows followed by low levels in subclinical mastitis cows. Plasma levels of their parameters were lowest (p<0.001) in healthy cows. Plasma progesterone levels were significantly higher (P<0.001) in healthy cows in comparison to group II and III cows. Plasma TNF-α, PGFM and progesterone levels showed significant (P<0.001) variations between days and between groups I and group II cows whereas NO, IL-8 and cortisol levels did not change.
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