National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Musculoskeletal injuries existed throughout human history.“Fracture” defined as a break in the continuity of the bone. Prolonged period required for healing of fractures entails much suffering & economic loss to the patient. Varied products from vitamins to hormones - tried to hasten the process of bone healing - unfortunately without positive outcome. Arjun tree with its roots in Indian mythology, known to have good effects on bone healing from many centuries. Anabolic steroids, are a class of steroid hormones related to the hormone testosterone. They increases protein synthesis within cells, which results in the building up of cellular tissue. Except few studies, no extensive investigations have been made for improving this inherent biological phenomenon of bone healing. Hence, the research question was formulated as “whether the herb Arjuna terminalia & anabolic steroid induce favorable response in bone healing & to evaluate their fracture healing property radiologically. In our study we induce fracture in 16 wistar albino rats of either sex using 3-point bending method. Two treatment groups made as Terminalia arjuna & anabolic steroid group. Treatment given for 4 weeks & rats investigated radiologically for fracture healing phenomenon. Terminalia arjuna treated animals revealed faster initiation of healing process than anabolic steroid treated group. Healing was almost complete within four weeks of fracture in Terminalia arjuna treated animals & remained incomplete in anabolic steroid treated animals. Our study indicates - daily administration of an alcoholic extract of Arjuna terminalia orally in the dosage of 500mg/kg has definite action on the rate of healing of fractures.
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