International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:5, May, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(5): 377-391

Endophytes: The Producers of Important Functional Metabolites
Suriya Rehman*
Department of Biology, College of Science, University of Dammam, KSA
*Corresponding author

Natural product based compounds have immense impact on modern medicine. More than 50% of the new chemical products registered with FDA during 1981-2002 as anti-cancer agents, anti-migraine agents and anti-hypertensive agents were with natural products or derived thereof. Some possible sources of natural products include mostly plants, which are extensively being used by man and may lead to their permanent loss from habitat. This natural loss is important to the society for a number of reasons, including the maintenance of ecosystem, functioning and for ethical reasons and specifically important to pharmaceutical companies in their search for novel natural products. Amongst the plants being lost, will be some which have the ability to produce important, but as yet undiscovered bioactive molecules. Though efforts are on to conserve these important species involving insitu and exsitu cultivation and the search for microbial diversity associated with the plants known as endophytes. Endophytes are microorganisms (bacteria or fungi or actinomycetes) that dwell within robust plant tissues by having a symbiotic association. A large amount of bioactive compounds produced by them not only are useful for plants but also are of economical importance to humans. In this review, we have tried to comprehend the role of endophytes in the production of pharmaceuticals and agrochemicals.

Keywords: Endophytes, Pharmaceutical, Metabolites, Ecosystem.

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How to cite this article:

Suriya Rehman. 2016. Endophytes: The Producers of Important Functional MetabolitesInt.J.Curr.Microbiol.App.Sci. 5(5): 377-391. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.