International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2022 - IJCMAS--ICV 2022: 95.28 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020] For more details click here

Login as a Reviewer

See Guidelines to Authors
Current Issues
Download Publication Certificate

Original Research Articles                      Volume : 5, Issue:4, April, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(4): 1022-1035

Immuno-defense Strategy in Earthworms: A Review Article
Shruti Gupta and Shweta Yadav*
Department of Zoology, School of Biological Sciences, Dr. H. S. Gour University, Sagar, M.P., India
*Corresponding author

Earthworms are relatively well known group of soil invertebrates and represents significant  part of soil biomass. They are routinely exposed with variety of soil microorganisms as well  chemical toxicants. Earthworms have developed powerful immunodefense system to  potentially escape from pathogenic environment by evoking the immune system and to maintain the self integrity. Earthworm emerges as immuno-defense model because of their  strong, well developed innate immuno-defense mechanism strategy against stressed  environment. Coelomic cavity of earthworm consists immunocytes/coelomocytes, homologous to vertebrate’s leukocytes. Their immunity may potentially involved in detoxification of chemicals including, metal contaminants, pesticides and removal of pathogenic microbes. Their immuno-defense mechanism activates cellular signaling cascade  at exposure of contaminants including, nanoparticles by releasing several factor like antimicrobial peptides, PAMPs (pathogen associated molecular pattern), cytotoxic molecules, serine protease pathways. This review aims to understand important cellular and humoral  pathways to develop immuno-defense strategy in earthworms that may assist in detoxification  of toxicants.

Keywords: Earthworm, immune-defense, toxicants, exposure, detoxification, immunocytes

Download this article as Download

How to cite this article:

Shruti Gupta and Shweta Yadav. 2016. Immuno-defense Strategy in Earthworms: A Review Article.Int.J.Curr.Microbiol.App.Sci. 5(4): 1022-1035. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.