International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:4, April, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(4): 897-903

Isolation of Urinary Tract Pathogens and Study of their Drug Susceptibility Patterns
Richa Mishra*, Deepti Saksena and Vinoy K. Shrivastava
Department of Biosciences, Barkatullah University, Bhopal, 462026 (M.P.), India
*Corresponding author

The objective of present study was to analyze urine specimen of patients suffering from UTI for the identification of pathogenic organisms and their drug susceptibility patterns. A total of 1255 (897 females and 358 males) patients with clinical symptoms of UTI were included in the study. Automated bioMérieux VITEK 2 compact bacterial identification and antibiotic susceptibility analyzer is used in the present study. A total of 1255 urine samples were collected and out of these 400 were growth positive isolates. Out of these isolates Escherichia coli (42.5%) was found to be the most frequent causative agent of UTIs followed by Klebsiella spp (23.25%), Pseudomonas spp. (12.5%) and Enterobacter spp.  (9.75%), Candida spp. (5%), Staphylococcus aureus (3%), Acinetobacter spp. (2.5%) and Proteus (1.5%). All urinary isolates of E.coli including multidrug resistant strains were found to be highly sensitive for nitrofuratoin and pazufloxacin. Women are more prone towards UTI and E. coli is the main causative organism. The change in drug susceptibility pattern is notable since older drugs no longer show effectiveness, this is due to resistance developed by overuse or misuse of drugs. Comparative study should be repeated after regular intervals of time so that the changing patterns can be noted and choice of drug can be selected accordingly.

Keywords: Urinary Tract Infections,Drug Resistance, Bacterial Pathogens,E. coli, Antimicrobial Susceptibility Pattern.

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How to cite this article:

Richa Mishra, Deepti Saksena and Vinoy K. Shrivastava. 2016. Isolation of Urinary Tract Pathogens and Study of their Drug Susceptibility PatternsInt.J.Curr.Microbiol.App.Sci. 5(4): 897-903. doi:
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