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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:4, April, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(4): 820-824
DOI: http://dx.doi.org/10.20546/ijcmas.2016.504.094


Speciation and Antifungal Susceptibility Pattern of Candida Isolated from Clinical Specimens
S. Mohan* and D. Karthikeyan
Department of Microbiology, Vinayaka Missions Medical College and Hospital, Karaikal-609609  Puducherry, India
*Corresponding author
Abstract:

Candidiasis is one of the major fungal infections among hospitalized and   immunocompromised patients. Identification of Candida upto species level is required as there is increase in the incidence of non albican Candida infections. Increased incidence of antifungal resistance has also been reported. Hence, this study was aimed at speciation of candida and their antifungal susceptibility from clinical specimens. A total of 93 Candida isolated from various clinical specimens. Candida Speciation was performed using CHROM agar and conventional methods. Antifungal susceptibility test was performed as per CLSI recommendations in document M44-A. Candida albicans (39.78%) was found to be the predominant species isolated from clinical specimens followed by non albican candida. Among non albican candida, C.tropicalis (22.58%) was predominant species isolated. C.albicans (45.95%) and  C.tropicalis(38.09%) showed least sensitivity towards azole group. Majority of isolates remained susceptible to Amphotericin B. Candida albicans was found to be the predominant species isolated from clinical specimens. Among non albicans candida, Candida tropicalis was the predominant species isolated. Candida tropicalis was least sensitive to azoles followed by Candida albicans.


Keywords: Candida,CHROM agar, Antifungal susceptibility

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How to cite this article:

Mohan, S., and Karthikeyan, D. 2016. Speciation and Antifungal Susceptibility Pattern of Candida Isolated from Clinical Specimens.Int.J.Curr.Microbiol.App.Sci. 5(4): 820-824. doi: http://dx.doi.org/10.20546/ijcmas.2016.504.094
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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