International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:4, April, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(4): 741-749

Infectious Etiology of Acute Respiratory Distress Syndrome (ARDS) with Thrombocytopenia in Adults and their Antimicrobial Sensitivity Pattern
Pritam J. Pardeshi*, Anuradha S. De and Sujata M. Baveja
Department of Microbiology, L.T.M. Medical College & Hospital, Mumbai, India
*Corresponding author

Acute respiratory distress syndrome (ARDS) manifests as rapidly progressive dyspnea, tachypnea and hypoxemia. Diagnostic criteria include acute onset, profound hypoxemia, bilateral pulmonary infiltrates, and the absence of left atrial hypertension. To study the infective organisms and their antimicrobial susceptibility pattern among organisms isolated from Endo-tracheal (ET) aspirates in adult patients admitted to this hospital with ARDS and having thrombocytopenia. In this prospective study, 100 patients above 18 years, admitted in Intensive care Units and on ventilator in a tertiary care hospital were enrolled. Endotracheal secretion culture & blood culture were performed in all these patients. Out of total 100 patients, Endotracheal secretion culture positive was 76% and 35% was blood culture positive. In ET aspirates, Acinetobacter species was commonest (43.37%), followed by Klebsiella pneumoniae (18.07%) and Pseudomonas aeruginosa (16.86%). Overall susceptibility to amikacin was 24.4% and to cephalosporins was <2%. Susceptibility to imipenem was 89.3%. Overall carbapenem resistance was 10.7%. The need for diagnostic testing to determine the etiology of ARDS is essential so that management of patients with ARDS can be instituted promptly.

Keywords: Acute Respiratory Distress Syndrome (ARDS) with thrombocytopenia; Infectious etiology; Antimicrobial susceptibility (ABS) pattern

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Pritam J. Pardeshi, Anuradha S. De and Sujata M. Baveja. 2016. Infectious Etiology of Acute Respiratory Distress Syndrome (ARDS) with Thrombocytopenia in Adults and their Antimicrobial Sensitivity PatternInt.J.Curr.Microbiol.App.Sci. 5(4): 741-749. doi:
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