National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The integration of nanomaterials with biology is finding wide applicability in various areas of medical science. Silver has been long recognized as having inhibitory effect on various microorganisms present in medical and industrial processes. But silver nanoparticles (SNPs), when synthesized by wet chemical reduction method are found to be toxic, flammable and not at all environment friendly. Therefore in present study, an attempt was made to formulate a cost effective and environment friendly technique for green synthesis of SNPs, which were synthesized using extract of Carica papaya, Allium cepa and Azadirachta indica with AgNO3 solutions and their antibacterial activity against clinical isolates viz., Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Staphylococcus aureus and Steptococcus pyogenes isolated from bed sheets of casualty ward from Prince Aly Khan Hospital was studied using Disk Diffusion Method. The SNPs were then impregnated onto cotton bedsheets and their antibacterial activity on the same isolates was studied. The effect of consecutive washing of the coated disks with distilled water on the antibacterial property was also investigated. The antibacterial activity of the cotton bed sheet coated with SNPs of all the three extracts was found to be retained up to three consecutive washings. This work demonstrates the possible use of biologically synthesized SNPs incorporated in cotton bed sheets to minimize nosocomial infections.
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