National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Aim of the study is to identify and characterize the bioactive compounds from methanol leaf extract of Enicostemma axillare responsible for the bactericidal activity. The in vitro antibacterial activity was determined by disc diffusion method against Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis and Bacillus subtilis. Gas Chromatography-Mass Spectrometry (GC-MS) studies were carried out to identify the presence of bioactive compounds. Antibacterial studies reveal a dose-dependent zone of inhibition. A maximum zone of inhibition was observed with reference to Klebsiella pneumoniae (12mm) followed by Escherichia coli (10mm). Observation of GC-MS results shows the presence of antibacterial compounds glycine, N- methyl ester, octadecatrienoic acid, 1-heptatriacetanol, and tetramethyl-2-hexadecen-1-ol were identified. It is concluded that the methanolic leaf extract from Enicostemma axillare possesses the potential compounds responsible for the antibacterial activity.
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