National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Klebsiella spp exhibits an increased antimicrobial resistance by producing Extended Spectrum Beta Lactamases (ESBL) and Carbapenamases. Studying their resistance pattern will help in appropriate use of antibiotics and infection control. Aim of the study is to characterize Klebsiellae, to determine their antibiogram by disc diffusion, phenotypic detection of ESBL and carbapenemase. The study was conducted in the Department of Microbiology, K.S. Hegde Medical Academy, on the isolates of Klebsiella from samples of exudates, blood, CSF, body fluids, sputum and urine from October 2014 to April 2016. Klebsiellae were characterized and antibiotic susceptibility testing, phenotypic tests for ESBL and Carbapenemase production were done as per CLSI guidelines. Amongst 509 Klebsiella isolates, 93.3% were Klebsiella pneumoniae and 6.6% were Klebsiella oxytoca. Maximum susceptibility was to Meropenem (76.6%), Imipenem (75.83%). Maximum resistance (68.5% - 69.5%) was to the third generation Cephalosporins. Multi drug resistant Klebsiella comprised 28%, ESBL producers were 53.83% and 12.3% were Carbapenamase producers. Monitoring the ESBL and Carbapenamase production, for an effective antibiotic policy prevents MDR Klebsiellae and isolation by strict infection control prevents outbreaks.
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