National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Increasing resistance rates of bacteria against standard antibiotics has become great problem for the treatment of UTI. To fight with this problem, an old drug Nitrofurantoin getting good attraction. Action at multiple sites and achieving levels in urine is the major strength of Nitrofurantoin as well as tolerated orally well and Side-effects are very less. Methodology: Study was conducted in Microbiology Department from April 2016 to April 2017. Urine samples were collected from patient admitted in various wards and attending O.P.D. and transport to laboratory. Every urine specimen received in the Microbiology laboratory was processed according to the recommended procedures for the isolation and identification of bacterial isolates. Bacteria were identified by colony morphology, gram staining and biochemical test from the primary isolation plates. Antibiotic susceptibility testing done for each isolates by DDT of Kirby Bauer on Muller Hinton Agar according to CLSI guideline. 357 urinary isolates were recovered with significant count in study period. E. coli 213 (59.66%) was the commonest organism isolated followed by Klebsiella pneumoniae 46 (12.89%), Enterococcus spp 33 (9.24%). Nitrofurantoin susceptibility in our study for E. coli was 72.3%, Klebsiella spp. 30.6%, Enterococcus 69.71%, Staphylococcus aureus 85.71%, Enterobacter 60 % and CONS 100%. However Mariraj et al., (2016) found 80-90% susceptibility for all urinary isolates and Rajesh et al., (2010) found E. coli was 82%, Klebsiella spp. 92 %, Enterococcus 00.00%. In the present era of antibiotic resistance urinary isolates show very good susceptibility for nitrofurantoin as compare to other commonly use antibiotic for treatment.
Citations |
 |
 |
 |
 |
