National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Probiotics help maintain human health using different mechanisms. Recently, several reports have been published which deal with such beneficial action which is said to be obtained by the secretion of Lantibiotics. This study focuses on one Probiotic LAB culture isolated from our local niche. This LAB has revealed certain beneficial effects in aquaculture systems. Fourteen potent gastrointestinal pathogens were subjected to the presence of the probable Lantibiotic. Both qualitative and quantitative estimation of the activities was carried out and the antimicrobial activity was expressed in terms of either growth obtained and/or zone of inhibition in different treatments with the LAB originated bacteriocin. The bacteriocin was subjected to several temperature, pH and different salt concentration treatments in order to check its stability and efficacy under such conditions. A number of methods were used to concentrate the extract from the activated LAB. Purification was carried out using TLC as well as by adsorption-desorption method. The results indicate that the bacteriocin can be termed as probable lantibiotic which is quite effective against the gastrointestinal pathogens like Proteus vulgaris and Vibrio parahaemolyticus that have shown to be inhibited by our locally isolated, produced and partially purified LAB originated lantibiotic.
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