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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 14, Issue:3, March, 2025

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2025.14(3): 33-36
DOI: https://doi.org/10.20546/ijcmas.2025.1403.006


Clinical Spectrum, Molecular Assay and Genotyping of Hepatitis C Virus in a Tertiary Care Centre of Northern India
Pushkar, Paramjeet Singh Gill and Parveen Malhotra*
Department of Microbiology & Medical Gastroenterology, PGIMS, Rohtak, India
Department of Microbiology, PGIMS, Rohtak, India
*Corresponding author
Abstract:

Chronic hepatitis C virus (HCV) infection is a pan-global public health problem; our cross-sectional study over one year in 100 HCV-Ab positive patients whose mean age was 44.9 years showed predominance between 31 and 40 years. Genotype 3 was the most prevalent but maximum viral load was seen in genotype 1. Genotype 3 is most difficult to treat, hence it will be difficult to achieve a high sustained virological response with treatment.


Keywords: Hepatitis C Virus, Genotype, Epidemiology


References:

Chung RT. Acute hepatitis C virus infection. Clinical infectious diseases. 2005 Jul 1;41(Supplement1): S14-7. https://doi.org/10.1086/429490

Ministry of Family and Health Welfare (MOHFW) Government of India, National Guidelines for Diagnosis and Management of Viral Hepatitis. 2018. Available from: http://clinicalestablishments.gov.in/WriteReadData/3591

Ministry of Health and Family Welfare (MOHFW) Government of India, National Viral Hepatitis Control Program operational guidelines. 2018. Available from: https://www.inasl.org.in/national-viral-hepatitis-control-program.  

Ministry of Health and Family Welfare (MOHFW) Government of India, National Laboratory Guidelines for Testing of Viral Hepatitis Control. 2018. Available from: http://www.inasl.org.in/national-laboratory-guidelines.

Petruzziello A, Marigliano S, Loquercio G, Cozzolino A, Cacciapuoti C. Global epidemiology of hepatitis C virus infection: An up-date of the distribution and circulation of hepatitis C virus genotypes. World J Gastroenterol. 2016; 22(34):7824-40. https://doi.org/10.3748/wjg.v22.i34.7824

Shah SR, Rao PN, Sarin SK, Chowdhury A, Bhatia S, Dharamsi R. et al., Chronic hepatitis C virus infection in India. Regional demographics and distribution of viral genotypes. Ind J Gastroenterol. 2016;35(6):469–77. https://doi.org/10.1007/s12664-016-0709-1

Shepard CW, Finelli L, Alter MJ. Global epidemiology of hepatitis C virus infection. The Lancet infectious diseases. 2005;5(9):558-67.

https://doi.org/10.1016/s1473-3099(05)70216-4

Verma R, Behera BK, Jain RB, Arora V, Chayal V, Gill PS. Hepatitis C: A silent threat to the community of Haryana, India: A community-based study. AMJ. 2014; 7(1):11-16.

https://doi.org/10.4066/amj.2014.1883

WHO. Combating Hepatitis B and C to Reach Elimination by 2030. Available from: http://apps.who.int/iris/bitstream/handle/10665/206453/WHO_HIV_2016.

WHO. Hepatitis C. Availaible from: http://www.who.int/mediacentre/factsheets/details/hepatitis-C.   

Yabaji PM, Shankar kumar A, Shukla A, Bhatia S. Hepatitis C virus infection in a tertiary care hospital in Mumbai, India: Identification of a mixed and novel genotype. Indian J Med Microbiol 2018; 36:352-6. https://doi.org/10.4103/ijmm.ijmm_18_221  


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How to cite this article:

Pushkar, Paramjeet Singh Gill and Parveen Malhotra. 2025. Clinical Spectrum, Molecular Assay and Genotyping of Hepatitis C Virus in a Tertiary Care Centre of Northern India.Int.J.Curr.Microbiol.App.Sci. 14(3): 33-36. doi: https://doi.org/10.20546/ijcmas.2025.1403.006
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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