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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 14, Issue:3, March, 2025

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2025.14(3): 28-32
DOI: https://doi.org/10.20546/ijcmas.2025.1403.005


Deadly and Catastrophic Face of Chronic Hepatitis B
Chitrakshi Bhardwaj, Parveen Malhotra*, Vani Malhotra, Pranav Malhotra, Navya Malhotra and Ritwik Gupta
Department of Medical Gastroenterology and Obstetrics & Gynaecology, PGIMS, Rohtak, Haryana, VMCC & Safdarjung Hospital, HIMSAR, Hamdard Medical College & HAHC Hospital, New Delhi India
*Corresponding author
Abstract:

Hepatitis B virus (HBV) impacts large number of populations worldwide and has both hepatic and extrahepatic manifestations. It can present as acute hepatitis, chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC). The available data provide evidence that HBV infection is associated with the risk of developing HCC with or without an underlying liver cirrhosis, due to various direct and indirect mechanisms promoting hepatocarcinogenesis. We report a twenty-three-year-old male, not a known case of any chronic illness presented with distension of abdomen. On evaluation he was diagnosed to be having hepatitis B related cirrhosis of liver with hepatocellular carcinoma with portal vein thrombosis. His ultrasonogram showed altered echotexture of liver with suspicious lesions in both lobes of liver with ascites and portal vein thrombosis. On subjecting to Triple phase Computed tomography scan confirmed ultrasonography findings and suspicious lesions showed enhancement on arterial phase and wash out on venous and portal phase. His liver function tests were deranged, Alpha feto protein level (AFP) was significantly raised to 1050 I.U. and HBV DNA quantitative was one lakh I.U/ml. He was unmarried and on family screening his mother was found to be chronic hepatitis B but in inactive carrier stage. Hepatitis B has many presentations varying from inactive carrier stage in majority to cirrhosis and H.C.C but presenting for first time with H.C.C in such a young age is not common, thus making treating health professionals for becoming more vigil for such deadly and acute catastrophic face of Hepatitis B.


Keywords: Chronic hepatitis B, Hepatocellular carcinoma, vertical transmission, Ascites, Portal Vein thrombosis


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How to cite this article:

Chitrakshi Bhardwaj, Parveen Malhotra, Vani Malhotra, Pranav Malhotra, Navya Malhotra and Ritwik Gupta. 2025. Deadly and Catastrophic Face of Chronic Hepatitis B.Int.J.Curr.Microbiol.App.Sci. 14(3): 28-32. doi: https://doi.org/10.20546/ijcmas.2025.1403.005
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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