National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Background and Objective: There are lots of worms that live in the dirt. All persons, including the elderly, are frequently discovered to have soil-transmitted helminths (STH). This is so that the parasite can influence how the immune system reacts by elevating IgG4 antibody levels. A. lumbricoides antigen-specific antibodies are found in blood samples using the ELISA method's IgG4 detection. STH infection compromises the human immune system, leading to elevated immunoglobulin E (IgE) levels, eosinophilia, and the generation of T-helper 2 (Th2) cells, particularly in response to variations in TNF- α and IL-4 levels. The ascariasis and STH are detected in this evaluation using the A. lumbricoides IgG ELISA Kit, TNF- α, and IL-4 ELISA Kit. The purpose of this research is to ascertain the incidence of STH in adults inResults and Conclusion: There were 78 participants in this study; the most common age range was 46–55 years old (28 participants); the most prevalent sex was female (65 participants); 57 participants tested positive for IgG4; the majority of sufferers were in the 17–25 year age group (88.9%); and the majority were of the male sex (76.9%); the levels of TNF– α and IL–4 were checked, and they were found to be 18.9%. In this study, women between the ages of 46 and 55 make up the majority of the respondents. The majority of respondents were female and between the ages of 17 and 25, and less than half of them diagnosed ascariasis and STH.
Allen, R. M., J. E., & Maizels, “Diversity and dialogue in immunity to helminths. Nature Reviews Immunology,” vol. 11(6), no. 375–388., 2011, https://doi.org/10.1038/nri2992.
Al-Tameemi, R., Kanaan Kabakli, “Ascaris lumbricoides : Epidemiology, Diagnosis, Treatment, and Control. Asian Journal of Pharmaceutical and Clinical Research,” vol. 13(4), no. 8–11., 2020, https://doi.org/10.22159/ajpcr.2020.v13i4.36930.
CDC., 2020 “CDC - Ascariasis.”
Chen, C., F., Liu, Z., Wu, W., Rozo, C., Bowdridge, S., Rooijen, N. Van, Jr, J. F. U., Wynn, T. A., & William, 2012. “An essential role for the Th2-type response in limiting tissue damage during helmit infection. National Institute of Health,” vol. 18(2), no. 260–266. https://doi.org/10.1038/nm.2628.An.
Dunn, R. M., J. C., Turner, H. C., Tun, A., & Anderson, “Epidemiological surveys of, and research on, soil-transmitted helminths in Southeast Asia: A systematic review. Parasites and Vectors,” vol. 9(1), no. 1–13, 2016.
Gazzinelli-Guimaraes, P., “Helminths Parasites and Immune Regulation. F1000Research.,” vol. 7:1685, 2018.
Gowon, A. I., O. V. Baba, O. I. Baba, P. A. Akpu, and A. E. Lynda, “Ascaris lumbricoides Infection Using Microscopy and IgG4 Detection Techniques in a School Children Population in Central Nigeria: An Epidemiological Study,” J. Infect. Dis. Treat., vol. 04, no. 01, pp. 1–5, 2018, https://doi.org/10.21767/2472-1093.100042.
Hairani, B., “Helminth infection, immunity and allergy. Infeksi Cacing, Imunitas, Dan Alergi,” vol. 4(1), no. 47–52., 2012.
Hotez P J, Molyneux D H, Fenwick A, Kumaresan J, “No TitleControl of Neglected Tropical Disease.,” vol. 357, pp. 1018–1027, 2007.
Incani, E., R. N., Ferrer, E., Hoek, D., Ramak, R., Roelfsema, J., Mughini-Gras, L., Kortbeek, T., & Pinelli. Diagnosis of intestinal parasites in a rural community of Venezuela: Advantages and disadvantages of using microscopy or RT-PCR. Acta Tropica,”2017" vol. 167, no. 64–70. https://doi.org/10.1016/j.actatropica.2016.12.014
Juhairiyah, L. & Indriyati, 2016. Ascariasis in South Kalimantan. Journal of Health Epidemiology and Communicable Diseases. vol. 2(1), no. 1–6.
Lamberton, P. M., P. H. L., & Jourdan, “Human Ascariasis: Diagnostics Update. Current Tropical Medicine Reports,” vol. 2(4), no. 189–200., 2015, https://doi.org/10.1007/s40475-015-0064-9.
Min, B., “Basophils Produce IL-4 and Accumulate in Tissues after Infection with a Th2-inducing Parasite,” J Exp Med, vol. 200(4), pp. 507–17, 2004. https://doi.org/10.1084/jem.20040590
Naglaa., “Effect of Ascaris lumbricoides infection on T helper cell type 2 in rural Egyptian children. Journal of Therapeutics and Clinical Risk Management.,” vol. 12 379-385, 2016.
Nugraha, N., T. I., Semiarty, R., & Irawati, “Hubungan Sanitasi Lingkungan dan Personal Hygiene Dengan Infeksi Soil Transmitted Helminths (STH) pada Anak Usia Sekolah Di Kecamatan Koto Tangah Kota Padang.,” J. Kesehat. Andalas, vol. 8(3), no. 590, 2019, https://doi.org/10.25077/jka.v8i3.1046.
Nurhayati, N. I., Irawati, N., Darwin, E., & Lipoeto, “Relationship Between Interleukin-10, Cholesterol and Blood Glucose Levels in Geohelminth Positive Adolescents and Adults. Journal of Medical Sciences,” vol. 20(1), no. 18–23., 2020, https://doi.org/10.3923/jms.2020.18.23.
Pilotte, S. A., N., Maasch, J. R. M. A., Easton, A. V., Dahlstrom, E., Nutman, T. B., & Williams, “Targeting a highly repeated germline DNA sequence for improved real-time PCR-based detection of Ascaris infection in human stool. PLoS Neglected Tropical Diseases,” vol. 13(7), no. 1–16., 2019, https://doi.org/10.1371/journal.pntd.0007593.
Renanti, E. R., S. R. Rusjdi, “Hubungan Infeksi Soil Transmitted Helminth dengan Status Gizi pada Murid SDN 29 Purus Padang. Jurnal Kesehatan Andalas,” vol. 4(2), pp. 353–358., 2015.
Silver, S. S. R., Z. A., Kaliappan, S. P., Samuel, P., Venugopal, S., Kang, G., Sarkar, R., & Ajjampur, “Geographical distribution of soil transmitted helminths.,” no. 7–16., 2018. https://doi.org/10.1371/journal.pntd.0006153
Uneke, C., “No Title Soil transmitted helminth infections and schistosomiasis in school age children in sub-Saharan Africa: Efficacy of chemotherapeutic intervention since World Health Assembly resolution 2001’,” Tanzan. J. Health Res., vol. 12(1), p. 11, 2010.
Vlaminck, J., T. Supali, P. Geldhof, C. H. Hokke, P. U. Fischer, and G. J. Weil. 2016. Community Rates of IgG4 Antibodies to Ascaris Haemoglobin Reflect Changes in Community Egg Loads Following Mass Drug Administration. PLoS Negl. Trop. Dis., vol. 10, no. 3, pp. 1–18. https://doi.org/10.1371/journal.pntd.0004532.
Wiria, M., A. E., Djuardi, Y., Supali, T., Sartono, E., & Yazdanbakhsh, “Helminth infection in populations undergoing epidemiological transition: A friend or foe? Seminars in Immunopathology,” vol. 34(6), no. 889–901., 2012, https://doi.org/10.1007/s00281-012-0358-0.
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