National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Background: Hepatitis C virus infection in hemodialysis patients is mainly associated with prolonged vascular access, and contaminated equipment and as well as due to breakdown of universal precautionary procedures.The study aims on the prevalence of Hepatitis C Virus among hemodialysis patients by Enzyme Linked Immunoassay (ELISA) and Quantitative Hepatitis C RNA real Time PCR. Methods: This retrospective record-based study is done from January 2023to December 2023, A total of 191 patients on maintenance haemodialysis were screened and tested for anti-HCV antibodies by 3rd generation ELISA and quantitative HCV RNA detection by real time-PCR as per CDC guidelines. Results: Out of 191, Anti-HCV antibodies were positive in 27patients, comprising 20 (74%) males and 7 (26%) females. HCV RNA was detected in 20patients, 16(80%) males and 4(20%) females, with highest prevalence among 41-60 years (55%). Conclusion: This study can help health professionals to treat patients with HCV on hemodialysis more effectively. Also reinforces the need for establishing effective prevention programs, which could lead to a reduction in the prevalence of HCV among patients on hemodialysis. In the absence of vaccine, routine screening and adherence to standard testing protocol for current HCV infection, infection control practice is the key strategy for preventing HCV transmission in hemodialysis units.
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