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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Rosa gallica is an ornamental flowering plant commonly grown in gardens. The present study utilizes the hip of Rosa gallica for the extraction of phytochemicals for finding out its phytochemical constituents and biological properties like antimicrobial and antihemolytic activities. The hip extracts of Rosa gallica derived using the solvents, aqueous, ethanol, petroleum ether, acetone and benzene showed the presence of different phytochemicals like alkaloids, flavonoids, phenolics and steroids. The quantitative phytochemical assay of Rosa gallica hip extract revealed the presence of higher quantities of alkaloids, phenols and flavonoids in aqueous extract. The HPLC analysis of the extract revealed the presence of flavonoids – rutin, quercetin and genistein. The aqueous extract of Rosa gallica hips showed 2.1 cm and 2.0 cm zone of inhibition against the bacteria, Escherichia coli and Enterococcus faecalis, respectively at 1000 ppm concentration while the lower extract concentrations showed lower or no antibacterial activity. The extract of Rosa gallica hips revealed dose dependent antihemolytic activity with an IC50 value of 2.28 μg/ml. The results of the present study shows that the aqueous extracts of Rosa gallica hips may be used to develop good antibacterial and antihaemolytic drug.