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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 12, Issue:11, November, 2023

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2023.12(11): 270-277
DOI: https://doi.org/10.20546/ijcmas.2023.1211.023


Phytochemical Constituents, Antibacterial and Antihemolytic Activities of Rosa gallica
A. Sheela1,2 and T. M. Vijayalakshmi2*
1Department of Biochemistry, Valliammal College for Women, Anna nagar, Chennai 102, India 2Department of Medical Biochemistry, University of Madras, Taramani Campus, Chennai - 600 113, Tamil Nadu, India
*Corresponding author
Abstract:

Rosa gallica is an ornamental flowering plant commonly grown in gardens. The present study utilizes the hip of Rosa gallica for the extraction of phytochemicals for finding out its phytochemical constituents and biological properties like antimicrobial and antihemolytic activities. The hip extracts of Rosa gallica derived using the solvents, aqueous, ethanol, petroleum ether, acetone and benzene showed the presence of different phytochemicals like alkaloids, flavonoids, phenolics and steroids. The quantitative phytochemical assay of Rosa gallica hip extract revealed the presence of higher quantities of alkaloids, phenols and flavonoids in aqueous extract. The HPLC analysis of the extract revealed the presence of flavonoids – rutin, quercetin and genistein. The aqueous extract of Rosa gallica hips showed 2.1 cm and 2.0 cm zone of inhibition against the bacteria, Escherichia coli and Enterococcus faecalis, respectively at 1000 ppm concentration while the lower extract concentrations showed lower or no antibacterial activity. The extract of Rosa gallica hips revealed dose dependent antihemolytic activity with an IC50 value of 2.28 μg/ml. The results of the present study shows that the aqueous extracts of Rosa gallica hips may be used to develop good antibacterial and antihaemolytic drug.


Keywords: Medicinal plants, Phytochemicals, Antibacterial activity, aqueous extract, Antihemolytic activity

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How to cite this article:

Sheela, A.  and Vijayalakshmi, T. M. 2023. Phytochemical Constituents, Antibacterial and Antihemolytic Activities of Rosa gallica.Int.J.Curr.Microbiol.App.Sci. 12(11): 270-277. doi: https://doi.org/10.20546/ijcmas.2023.1211.023
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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