National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Invasive diseases due to Acinetobacter is an increasing problem in health care settings and especially in Intensive Care Units (ICU) worldwide. These organisms occur as components of commensal flora of man and animals and are therefore regular contaminants of hospital environment. Purpose-This prospective study was conducted at Indraprastha Apollo Hospitals, New Delhi in the Department of Microbiology and Respiratory and Critical Care Medicine to ascertain the role of Acinetobacter as a Pathogen in Healthcare Associated Pneumonia (HCAP) and Blood stream Infections(BSI). Findings-One hundred and eight consecutive, non repeat isolates of Acinetobacter species isolated from blood and respiratory tract were studied. Nineteen cases were identified together as Healthcare associated pneumonia (HCAP) and blood stream infections(BSI). By applying Fishers Exact Test,the colonization rate vs the infection due to Acinetobacter species rate was calculated to be 82.41% (BSI+HCAP) and 17.59% which was found to be significantly in in favour of colonization.(p- value0.001). Tracheostomy was a significant risk factor associated with the development of HCAP due to Acinetobacter species (p-value< 0.05)(Fishers Exact Test) while Immunosuppression (p-value≤0.05.) and presence of multiple catheters(p<0.05) were independent risk factors in BSI infections. Immunosuppression was found to be significantly higher in the BSI group compared to the Non-BSI group. Conclusion- This study shows that mere colonisation by Acinetobacter species should not be considered as an indication for antimicrobial treatment for the same as a very small proportion of Acinetobacter species was responsible for infection.
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