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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2022.11(8): 52-64
DOI: https://doi.org/10.20546/ijcmas.2022.1108.007


Screening of Phytochemicals against Multiple Drug Resistant Bacteria from Clinical Isolates
Manish Dattatraya Karekar1, Sumit Chavan1, Rajal Dave1*, Abhishek Chatla2, Mansi Kamble2,Richa Raut1 and Mukund Ambawade1
1Krsnaa Diagnostics Ltd.Mahavir Chowk, Chinchwad, Pimpri-Chinchwad, Maharashtra 411019
2Haribhai V.Desai College of Commerce, Arts and Science
*Corresponding author
Abstract:

Plants, a rich source of therapeutic compounds because its tremendous applications in the pharmaceutical industry. To find a new and effective antimicrobial compound from the selected plant, the solvents like methanol, Ethanol, Chloroform, Hexane, Xylene, and water were used to evaluate systematically. In vitro antimicrobial activity was performed using Multi-Drug Resistant (MDR) clinical isolates by Kirby Bauer Method. Solvent extracts showed more antimicrobial activity compared to aqueous extracts of both plants. Phytochemical analysis of Piper betel leaves showed the presence of Glycoside, Tannin, Terpenoid, Coumarin, Flavonoid, and Phenol whereas Achyranthes aspera roots were lacking Phenol and Tannin. Thus, present studies suggest the medicinal use of bioactive components from traditional plants Piper betel and Achyranthes aspera in the treatment of various infectious diseases.


Keywords: Piper betel, Achyranthes aspera, Phytochemical, Antimicrobial activity, MDR
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How to cite this article:

Manish Dattatraya Karekar, Sumit Chavan, Rajal Dave, Abhishek Chatla, Mansi Kamble, Richa Raut and Mukund Ambawade. 2022. Screening of Phytochemicals against Multiple Drug Resistant Bacteria from Clinical Isolates.Int.J.Curr.Microbiol.App.Sci. 11(8): 52-64. doi: https://doi.org/10.20546/ijcmas.2022.1108.007