National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The copper (II) complex [Cu(1,10-phen)(2,6-pyridinedicarboxamide)](NO3)2 has been synthesized and characterized by Fourier transform infrared spectroscopy (FT-IR), Ultraviolet-visible spectroscopy (UV), Electron paramagnetic resonance spectroscopy (EPR) and Photoluminescence (PL) analysis. The copper complex was connected to two sides, 1,10-phenanthroline and 2,6 py-dicarboxamide ligands, providing a five-coordinate Cu (II) complex. The commercial heterocyclic base coordinated copper metal complex was found to have antimicrobial activity against Gram-positive and gram-negative bacteria. It is noted that the commercial ligand with a copper metal complex was found to be more biologically active, and the DNA-binding properties of the copper complex were investigated by UV, PL, and cyclic voltammetry measurements. The obtained results indicate that the Cu (II) complex binding in DNA through an intercalation mode and the binding constant (Kb) value of the complex as 1.9 × 104 M−1, respectively.
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