'' '' '' '' Study on Effect of Filgrastim in Severe Leukopenia Condition in Dogs
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles                      Volume : 11, Issue:3, March, 2022

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2022.11(3): 218-222
DOI: https://doi.org/10.20546/ijcmas.2022.1103.026


Study on Effect of Filgrastim in Severe Leukopenia Condition in Dogs
Koppula Anusha iD 1*, Basiri Dinesh2, Keshamoni Ramesh3, Jupaka Shashankand K. Mohanambal3
1Department of Veterinary Parasitology, 2Department of Veterinary Surgery and Radiology,
3Department of Veterinary Medicine, College of veterinary science, PVNRTVU, Rajendranagar, Hyderabad – 500030, Telangana, India
*Corresponding author
Abstract:

Filgrastim is a recombinant Methionyl Human Granulocyte- Stimulating Factor (r-metHuGCSF) analog used to stimulate the proliferation and differentiation of granulocytes in humans. Young pups and kittens suffer from severe leukopenia and neutropenia condition (etiology may be viral or bacterial or parasitic). Neutrophils being first line of defense in immunity system and decreased count may lead to increased mortality. In the present investigation 3 dogs with severe leukopenia and neutropenia condition when treated dogs with Filgrastim @ 10 μg/ kg b.wt. s.c daily for three days along with other supportive treatment, was found to be effective in correcting the hematological parameters within 48 hours of last dose of treatment and all those showed fast recovery also.


Keywords: Filgrastim, Leukopenia, neutropenia, hematological parameters
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How to cite this article:

Anusha, K., B. Dinesh, K. Ramesh, J. Shashank and Mohanambal, K. 2022. Study on Effect of Filgrastim in Severe Leukopenia Condition in DogsInt.J.Curr.Microbiol.App.Sci. 11(3): 218-222. doi: https://doi.org/10.20546/ijcmas.2022.1103.026
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.