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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(11): 97-103
DOI: https://doi.org/10.20546/ijcmas.2021.1011.013


Neonatal Septicemia and Drug Resistance; 2 Year Prospective Study
R. P. Lakshmi, V. L. Jayasimha, K. G. Raghukumar, C. S. Vinod Kumar, Satish S. Patil and K. G. Basavarajappa
R. P. Lakshmi, V. L. Jayasimha, K. G. Raghukumar, C. S. Vinod Kumar, Satish S. Patil and K. G. Basavarajappa
*Corresponding author
Abstract:

Neonatal sepsis is a worldwide problem with the prevalence at 1 to10 per 1000 live birth and one of the indicator for measuring the health status of a nation. According to WHO there are about 5 million neonatal death per year with 98% occurring in developing countries. Antimicrobial resistance is a growing threat worldwide. Blood culture is considered as the gold standard technique for diagnosis of neonatal septicemia. The main objectives includes, to know the various bacteria causing neonatal septicemia and their antibiogram. To detect drug resistance among the isolated bacteria. A Prospective study was done over a period of 2 year. Blood samples for culture were collected aseptically before starting antibiotic therapy and subcultures were performed. The isolates were identified by standard biochemical tests and antibiogram of the isolates were studied. Out of 360 cases 160 were bacteriologically positive, Klebsiella was the most common organism isolated (21%), followed by Staphylococcus aureus (20%) Acinetobacter (15%), Pseudomonas (13%). Maximum sensitivity was seen by Linezolid, Erythromycin for Gram positive organisms and Gram negative organisms were sensitive to Piperacillin/ Tazobactum, Imipenem, Levofloxacin, Meropenem. Knowledge of likely causative organism causing neonatal septicemia can help in instituting prompt and appropriate therapy which in turn reduce morbidity and mortality.


Keywords: Neonatal septicaemia, morbidity, antibiotics, microbiological investigation
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How to cite this article:

Lakshmi, R. P., V. L. Jayasimha, K. G. Raghukumar, C. S. Vinod Kumar, Satish S. Patil and Basavarajappa, K. G. 2021. Neonatal Septicemia and Drug Resistance; 2 Year Prospective Study.Int.J.Curr.Microbiol.App.Sci. 10(11): 97-103. doi: https://doi.org/10.20546/ijcmas.2021.1011.013