National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Sixty-four sera samples were collected from 25- and 45-days old puppies [16 puppies each from vaccinated (Group I) and unvaccinated (Group II) dam] brought to Immunization Unit, Madras Veterinary College Teaching Hospital, Chennai. The samples were subjected to functional antibody assay (SNT) and commercially available Indirect ELISA to know the kinetics of maternal derived antibody (MDA) against canine distemper. The mean MDA titre in Group I puppies were found as 4.38 ± 1.41 and the ELISA titre were 30 - 60 and 10–30 AU on 25 and 45 days of age respectively whereas the Group II (MDA-UV) had titre value of0.33 ± 0.60 and 0 by SNT (SN50) and ≤ 10 and ≤ 3 AU by Indirect ELISA on 25 and 45 days of pups respectively. Though the statistical analysis (Mann-Whitney test) revealed a significant difference (P<0.01) between MDA of two groups with none of the group member had required protective titre, this study strongly suggests that the dogs aged more than 4 weeks needs to be immunized against CDV in endemic region in view of eliciting protective titre at earlier with a view of avoiding window period of susceptibility between 25 and 45 days of age.
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