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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(11): 43-47
DOI: https://doi.org/10.20546/ijcmas.2021.1011.006


Kinetics of Maternal Derived Antibody Status against Canine Distemper in Pups
Bhambhani Mitali Inder1, M. Asok Kumar1*, A. Ramesh2, N. R. Senthil1, K. Srinivas3, T. Deviand P. Revathi1
1Department of Veterinary Preventive Medicine, Madras Veterinary College, TANUVAS, Chennai, Tamil Nadu, India
2Vaccine Research Centre – Viral Vaccines, Centre for Animal Health Studies, TANUVAS, Chennai, Tamil Nadu, India
3Indian Immunologicals Ltd. (NDDB), Hyderabad, India
*Corresponding author
Abstract:

Sixty-four sera samples were collected from 25- and 45-days old puppies [16 puppies each from vaccinated (Group I) and unvaccinated (Group II) dam] brought to Immunization Unit, Madras Veterinary College Teaching Hospital, Chennai. The samples were subjected to functional antibody assay (SNT) and commercially available Indirect ELISA to know the kinetics of maternal derived antibody (MDA) against canine distemper. The mean MDA titre in Group I puppies were found as 4.38 ± 1.41 and the ELISA titre were 30 - 60 and 10–30 AU on 25 and 45 days of age respectively whereas the Group II (MDA-UV) had titre value of0.33 ± 0.60 and 0 by SNT (SN50) and ≤ 10 and ≤ 3 AU by Indirect ELISA on 25 and 45 days of pups respectively. Though the statistical analysis (Mann-Whitney test) revealed a significant difference (P<0.01) between MDA of two groups with none of the group member had required protective titre, this study strongly suggests that the dogs aged more than 4 weeks needs to be immunized against CDV in endemic region in view of eliciting protective titre at earlier with a view of avoiding window period of susceptibility between 25 and 45 days of age.


Keywords: Canine Distemper- MDA- SNT and ELISA- Puppies immunization
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How to cite this article:

Bhambhani Mitali Inder, M. Asok Kumar, A. Ramesh, N. R. Senthil, K. Srinivas, T. Devi and Revathi, P. 2021. Kinetics of Maternal Derived Antibody Status against Canine Distemper in Pups.Int.J.Curr.Microbiol.App.Sci. 10(11): 43-47. doi: https://doi.org/10.20546/ijcmas.2021.1011.006