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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(7): 598-609
DOI: https://doi.org/10.20546/ijcmas.2021.1007.065


Mucormycosis and COVID-19: A Narrative Review
Sharique Ahmad1*, Shivani Singh1, Saeeda Wasim2, Mohd. Anwar3,Huma Parveenand Samarth Kaushik Kumar Shah4
1Department of Pathology, Era's Lucknow Medical College and Hospital, Era University, Lucknow, Uttar Pradesh-226003, India
2Nova IVF Fertility, Hazratganj, Lucknow, U.P. - 226001, India
3Department of Transfusion Medicine, SGPGI, Lucknow, Uttar Pradesh – 226003, India
4American University of Barbados, Wildey, Saint Michael, Barbados, BB11100
*Corresponding author
Abstract:

Zygomycosis was identified as easy and comprehensive factor for 2 clinicopathological distinct infection, mucormycosis resulted due to Mucorales and entomophthoramycosis occur due to order Entomophthorales of class Zygomycota. The name Zygomycosis has been used as similar word only for mucormycosis. As mucormycosis is systemic fungal infection occurs in patients debilitated from metabolic or immune disorders. The changes in taxonomic classification and 3 of Zygomycota and disease Zygomycosis had been described. The Mucormycosis infection had been involved in patients with COVID-19 but its epidemics and diagnosis in patients are not exactly known. The cases of mucormycosis resulted due to post COVID-19 effect known till now helps in recognizing the risk factors, clinical features and outcome. It shows vulnerability towards the patients with comorbidities of diabetes mellitus mainly one with imperfect diabetes mellitus regulation and severe COVID-19 infection. Its presentation was severe in poorly regulated diabetes mellitus mainly rhino and cerebral orbital pathological symptoms. This fungal infection is fatal and occurs mainly in individuals with suppressed immune system due to diabetes mellitus, transplantation elevated serum level with iron and several other diseases which decrease our immune response had enhanced the risk of mucormycosis. The new treatment have to be strategizes urgently for understanding the pathogenesis of mucormycosis and response of host cell for penetrating the hyphae which will give the target for new therapeutic involvement. Currently the knowledge about the characters of the pathogen to multiply in host cell is the commonly known etiological factor for this fungal infection which Rhizopus oryzae. As the patients with higher level of serum and available iron are particularly prone towards the disease mucormycosis. This infection are extremely angioinvasive prominently involved with capability of organism for acquiring iron through host cell and interaction with endothelial cells of outer layer of blood vessels. Many strategies are in pre-clinical stage for identifying the exact diagnosis and prognosis of disease.


Keywords: Mucormycosis, COVID-19, Immunosuppressed, Diabetes mellitus
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How to cite this article:

Sharique Ahmad, Shivani Singh, Saeeda Wasim, Mohd. Anwar, Huma Parveen and Samarth Kaushik Kumar Shah. 2021. Mucormycosis and COVID-19: A Narrative Review.Int.J.Curr.Microbiol.App.Sci. 10(7): 598-609. doi: https://doi.org/10.20546/ijcmas.2021.1007.065