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PRINT ISSN : 2319-7692 Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Zygomycosis was identified as easy and comprehensive factor for 2 clinicopathological distinct infection, mucormycosis resulted due to Mucorales and entomophthoramycosis occur due to order Entomophthorales of class Zygomycota. The name Zygomycosis has been used as similar word only for mucormycosis. As mucormycosis is systemic fungal infection occurs in patients debilitated from metabolic or immune disorders. The changes in taxonomic classification and 3 of Zygomycota and disease Zygomycosis had been described. The Mucormycosis infection had been involved in patients with COVID-19 but its epidemics and diagnosis in patients are not exactly known. The cases of mucormycosis resulted due to post COVID-19 effect known till now helps in recognizing the risk factors, clinical features and outcome. It shows vulnerability towards the patients with comorbidities of diabetes mellitus mainly one with imperfect diabetes mellitus regulation and severe COVID-19 infection. Its presentation was severe in poorly regulated diabetes mellitus mainly rhino and cerebral orbital pathological symptoms. This fungal infection is fatal and occurs mainly in individuals with suppressed immune system due to diabetes mellitus, transplantation elevated serum level with iron and several other diseases which decrease our immune response had enhanced the risk of mucormycosis. The new treatment have to be strategizes urgently for understanding the pathogenesis of mucormycosis and response of host cell for penetrating the hyphae which will give the target for new therapeutic involvement. Currently the knowledge about the characters of the pathogen to multiply in host cell is the commonly known etiological factor for this fungal infection which Rhizopus oryzae. As the patients with higher level of serum and available iron are particularly prone towards the disease mucormycosis. This infection are extremely angioinvasive prominently involved with capability of organism for acquiring iron through host cell and interaction with endothelial cells of outer layer of blood vessels. Many strategies are in pre-clinical stage for identifying the exact diagnosis and prognosis of disease.
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