Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

See Guidelines to Authors
Current Issues
Download Publication Certificate

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(7): 452-456
DOI: https://doi.org/10.20546/ijcmas.2021.1007.050


Isolation and Speciation of Candida Species from Oral Thrush in HIV Seropositive Individuals from Tertiary Care Hospital
Mariraj Jeer* and S. Vidyaa Nayaki
Department of Microbiology, Vijayanagar Institute of Medical Science, Ballari, India
*Corresponding author
Abstract:

Infection due to Candida species are increasing in recent decades, probable reason being increase in incidence of immunosuppression, significant risk being low absolute CD4+ T lymphocyte count. Increase in frequency of non Candida albicans species has been observed. Hence the present study was carried out to study the incidence of Candida species among HIV positive patient. Prospective study was carried on 100 HIV seropositive individuals presenting with oral thrush. Identification of Candida species was done using KOH mount, Gram’s stain and inoculated on Saboraud dextrose agar, CHROM agar and various other tests were carried out.CD4+ T cell count was done. the common age group affected was 16-45 years, with slight male preponderance. Most of the case fall either in stage 3 or stage 4. C.albicans was the predominant pathogen isolated accounting for nearly 52%, among the non albicans group the most common isolates were C.dubliensis (24%), C.tropicalis (15%), C.krusei (5%) and C.parapsilosis (4%). Nearly 70% of the patients had a CD4+ T- cell count of less than 200cells/µL. Candida is most common opportunistic fungal pathogen seen in HIV seropositive individual, when the CD+4 count is considerably low. Though, C.albicans most common pathogen isolated, there is also a significant increase in non Candida albicans species.


Keywords: Candida, non albicans Candida species, immuno suppression, oral thrush, CD4+ T cell
Download this article as Download

How to cite this article:

Mariraj Jeer and Vidyaa Nayaki, S. 2021. Isolation and Speciation of Candida Species from Oral Thrush in HIV Seropositive Individuals from Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 10(7): 452-456. doi: https://doi.org/10.20546/ijcmas.2021.1007.050