National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Nowadays Coagulase-negative staphylococci (CoNS) are the most common causes of device related infections, especially in extreme age group of patients such as neonates and old age. The antibiotic resistance and biofilm production of CoNS produce negative impact on clinical outcome of patients, The study is therefore conducted to determine the antimicrobial susceptibility pattern and surface adherence property of CoNS isolated from various clinical specimens.. During the six months study period 46 CoNS were isolated from various clinical specimens Staphylococcus epidermidis (47%) was the common isolate followed by Staphylococcus haemolyticus (24%), and Staphylococcus saprophyticus (24%). CoNS isolates showed maximum resistance to Ampicillin (76%), Clindamycin(74%), Cotrimoxazole (74%) and Erythromycin(72%). CoNS isolates revealed 100% sensitivity to Vancomycin. 72% of CoNS isolates showed Methicillin resistance and 61% were biofilm producers by Congo Red Agar method. Methicillin resistance and Biofilm production of CoNS lead to increased morbidity and mortality in hospitalized patients. Aseptic management should be followed in intravascular devise insertion and other invasive procedures to reduce the spread of CoNS infection.
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