National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
In the recent years, there has been an increased incidence and prevalence of extended spectrum beta-lactamase (ESBL) producing organisms all over the world and also in various parts of India. ESBL producers pose unique challenges to clinical microbiologist as well as clinicians. As multi drug resistance is rampant, the current study was undertaken to know the prevalence of ESBL producing Enterobacteriaceae in our tertiary health care centre. This study was carried out on 120 urine specimen collected from catheterized patients, aged between 20-70 yrs. The screening for ESBL production was done by the disc diffusion test as recommended by the Clinical and Laboratory Standards Institute(CLSI) and confirmed by the phenotypic disc confirmatory test (PDCT) and ESBL Hi Crome agar(Hi media-Mumbai). 28 specimen were culture positive among 120 samples. Escherichia coli (41.17%) was the most common isolate, followed by Klebsiella pneumoniae (35.29%). ESBL production was observed in 15(88.2%) isolates. The isolates of Escherichia coli (40%) were the most common ESBL producers, followed by Klebsiella pneumoniae (33.33%) and others. All isolates were sensitive to imipenem. There is a high prevalence of ESBL production in our hospital. Specific tests to detect ESBL production should be done routinely and an empirical therapy policy should be applied to the high risk units, based on the prevalence of the ESBL producing Enterobacteriaceae.
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